Parkinson’s disease was classified by Khon Weyer in five stages. Their classification is based on the severity of the symptoms and degree of disability experienced by the patient.
When describing treatment in parkinsons clinic, the neurologist, among other things, will take into account the stage at which the patient is considered. Early signs of Parkinson’s disease are usually invisible and appear gradually. If you have this condition, you may tire a lot or feel weak. It can also be shaking or shallow speech or changes in handwriting early signs of the disease.
The first stage is called a single disease. The term means that only one side of the body shows symptoms of Parkinson’s disease.
This is an early stage of the disease and can last for several years. Neuropathy is common at this stage. This treatment aims to prevent further damage to the nervous system.
Vitamin E was used at this stage, but many researchers believe it is not very useful. It has been shown that a selective MAO-B inhibitor is called Rasagiline and is promising.
The second stage of Parkinson’s disease is a bipolar disease. This means that the symptoms of Parkinson’s disease now appear on both sides of the body.
The disease is believed to be in the second stage, even if there are secondary symptoms (e.g., an occasional jolt) on this side of the body that has not had any symptoms.
Modern treatments at this stage include the use of dopamine stimulants. Until a few years ago, dopamine agonists were used only in the late stages of the disease. At present, researchers believe that if this treatment starts early, complications of drug use such as levodopa may not occur in later stages.
The disease is believed to be in the third stage, when symptoms develop, especially when the patient has difficulty maintaining the condition. Symptoms at this stage include instability and positivism.
Traditionally, dopamine or levodopa agonists have been described at this stage, however, as mentioned above, some of these drugs are now used in previous stages.
Stage 4 occurs when there is an increase in symptoms, including postural instability and fall. Surgery is one of the treatment options at this stage. Surgery may relieve some symptoms. However, as a general rule, it is recommended only for young patients who are healthy.
Stage 5 is the most advanced stage of Parkinson’s disease. The patient is usually attached to wheelchairs. Walking is only possible with the help of.
Levodopa is still the drug prescribed at this stage, along with the COMT inhibitor, which provides a longer lasting effect. Surgery may also be an option, including the abdominal incision, which destroys a small group of brain cells. This helps to avoid the stiffness that often occurs with Parkinson’s disease and can also stop the tremor.
Another possible treatment is deep stimulation of the brain when electrodes are implanted in brain tissue and stimulated by low-level electric currents.Symptoms of Parkinson’s disease develop when the patient moves from one stage to another. Current research produces new treatments, including stem cell transplantation and new drugs.